Masaryk University Entrance Exam 2027: Complete Preparation Guide

Grouped from the official Chemistry syllabus's continuous paragraphs. The 2022 sample paper front-loads calculation work and closes on biomolecules and metabolism.

• Atomic structure and the periodic table: subatomic particles, atomic and mass numbers, isotopes, the electron configuration of the elements, the successive filling of energy sublevels and orbitals, valence electrons, s, p and d elements, the Periodic Table and the established names of some groups, the periodicity of the properties of the elements, the positions of the representative elements, the transition d and f elements, and the locations of metals and nonmetals
• Stoichiometry and chemical equations: relative atomic mass and molecular mass, amount of substance and the mole, Avogadro's constant, the diatomic elements, molar mass, the molar volume of gases at standard temperature and pressure, the names and formulas of common inorganic ions and compounds in both directions, stoichiometric calculations from chemical formulas, mass percentage composition, chemical equations and balancing, mass relations in reactions, and calculations of reacting masses, amounts of substance and volumes of gases from equations
• Chemical bonding and molecular shape: chemical bonds and the octet rule, single and multiple covalent bonds, the coordinate covalent bond, the typical numbers of covalent bonds for nonmetals, the spatial orientation of covalent bonds, hybridization of atomic orbitals, the shapes of simple molecules, the polar covalent bond, electronegativity, polar and nonpolar molecules, the ionic bond and ionic compounds, and weak intermolecular bonding including the hydrogen bond
• Solutions and electrolytes: expressing the composition of solutions as mass fraction, amount-of-substance concentration and mass concentration with the calculations behind them, conversions involving density and parts per million, the equivalent amounts of acids and bases required for neutralization, titration of an acid with a base, solutions of nonelectrolytes and electrolytes, dissociation and ionization, strong and weak electrolytes, and the concentrations of ions in solutions of strong electrolytes
• Acids, bases and pH: the types of chemical reaction, protolytic reactions, the Brønsted definition of acids and bases, conjugate pairs, amphoteric compounds and ions, strong acids and bases, weak acids and bases with their ionization constants, the ionization of water and the ionic product of water, hydrogen ion concentration and the pH value, calculations for solutions of strong acids and bases from a given concentration or pH, the hydrolysis of ions, and the classification of aqueous salt solutions as acidic, alkaline or essentially neutral
• Redox reactions: oxidation-reduction reactions, oxidation numbers, oxidizing agents and reducing agents, recognising a redox reaction among non-redox alternatives, balancing redox equations, half equations and the numbers of electrons lost or gained, redox pairs and dehydrogenation
• Thermochemistry, kinetics and equilibrium: heats of reaction and other enthalpy changes, Hess's law, reaction rate and the factors that influence it, chemical equilibrium and equilibrium constants, the general relationship between the equilibrium concentrations of reactants and products, and the effect of changes in temperature, concentration and pressure on equilibria
• Chemistry of the elements: hydrogen and oxygen and their properties, ionic and covalent hydrides and oxides, acid-forming, basic and amphoteric oxides, water, the characteristics of chlorine, sulphur, nitrogen, phosphorus, carbon, silicon, the alkali metals, the alkaline earth metals, iron, copper, aluminium and zinc, their important compounds including oxides, hydroxides, covalent hydrides, oxyacids and salts, and the solubility of common salts
• Organic structure, isomerism and nomenclature: the bonds in organic compounds and the typical properties of organic compounds, the types of reaction in organic chemistry including addition, elimination, dehydration, condensation, hydrolysis, oxidation and reduction, the notation of structural and abbreviated (rational) formulas, structural isomerism and stereoisomerism, centres of chirality, systematic IUPAC nomenclature with functional and substitutive names, and the trivial and semisystematic names of the most common compounds
• Hydrocarbons and functional groups: hydrocarbons and the groups derived from them, saturated and unsaturated hydrocarbons, arenes and their typical reactions, organic halides, nitrocompounds, amines and their basicity, the formation of amides, alcohols and phenols with esterification, ethers, the oxidation of alcohols and quinones, aldehydes and ketones with oxidation, reduction and acetal formation, carboxylic acids and the reactivity of the carboxyl group, the common mono- and dicarboxylic, saturated and unsaturated, hydroxy- and keto-acids, and the names for acyls, acid halides, anhydrides, esters, amides, nitriles and urea
• Heterocycles and nucleic acids: the names and structures of the common types of heterocyclic compound, the purine and pyrimidine bases of nucleic acids, uric acid, the components of nucleosides and nucleotides and the bonds connecting them, phosphodiester bonds in polynucleotides, the DNA double helix, and the function of DNA and of the three major types of RNA in the transcription of the genetic code and in protein biosynthesis
• Saccharides and lipids: the classification and biological importance of saccharides, the structure of monosaccharides as acyclic oxo-forms and hemiacetal cyclic forms, anomers, the formation of glycosides, reducing and non-reducing disaccharides, polysaccharides, the fatty acids bound in lipids including the essential ones, acylglycerols, the hydrolysis of fats and oils, saponification and soap, the main constituents of phospholipids, the steroid ring system and the biological roles of the main sorts of steroid compound
• Amino acids and proteins: the structures and the common and systematic names of the twenty standard proteinogenous amino acids, the polarity and charge of the side chains at physiological pH, the peptide bond, the primary structure of proteins and the general features of secondary, tertiary and quaternary structure, disulfide cross-links, hydrogen bonds and other noncovalent stabilising interactions, the denaturation of proteins, and the two main classes of proteins
• Enzymes, vitamins and metabolism: the six main classes of enzymes, the important hydrolases of the digestive tract, the common chemical names of the vitamins, the anabolic and catabolic character of metabolic pathways, the importance of biological oxidations in the catabolism of nutrients, high-energy (macroergic) compounds and the energetic yield of metabolism, glycolysis and its intermediates, the role of the citric acid cycle and of the mitochondrial electron-transport chain, the end products of anaerobic and aerobic glucose degradation, β-oxidation of fatty acids, and the nitrogenous end products of amino acid and purine catabolism

The official syllabus's six headed sections are preserved; cell biology, genetics and human biology are each subdivided because a single pool for any of them would cover too much of a 40-question paper.

• Classification and diversity of life: a brief survey of the classification system, acellular, unicellular and multicellular organisms, the basic characteristics of vertebrata and mammals, and the milestones in biology and medicine with the scientists behind them
• Microorganisms and medically important species: bacteria and cyanobacteria, viruses and their structure, the lytic and lysogenic cycles, medically important yeasts and molds, medically important plants and protozoa, medically important worms and insects, and the causative agents of common infectious diseases with their transmission
• Chemical composition of the cell: the chemical composition of the cell, the structure and function of proteins, the structure and function of nucleic acids, and saccharides and lipids in the cell
• Cell structure and organelles: cell theory, the basic differences between prokaryotic and eukaryotic cells, biomembranes and membrane organelles with their structure and function, the secretory pathway through rough endoplasmic reticulum, Golgi apparatus and vesicles, lysosomes and ribosomes, energy transformation in mitochondria and chloroplasts, the cytoskeletal system, microtubules and microfilaments, cell movement, centrioles and basal bodies, and the structure of the cell nucleus
• Membrane transport: membrane transport, diffusion, osmosis and the behaviour of cells in hypotonic and hypertonic solutions, facilitated diffusion, active transport, endocytosis and exocytosis
• Cell cycle, mitosis and meiosis: the cell cycle and its phases, mitosis and its significance, meiosis I and II and how they differ from mitosis, the segregation and recombination of chromosomes in diploid organisms, crossing over, independent assortment, nondisjunction, stem cells, cell differentiation and the cancer cell
• Molecular genetics and gene expression: genetic information in DNA, RNA and protein, the expression of genetic information, semi-conservative DNA replication, transcription and translation, the genetic code, codons and exons, the gene and its expression, and prokaryotic and eukaryotic chromosomes and their structure
• Mendelian and human genetics: heredity and variability, the basic genetic terms, gene and genotype, allele, homozygote and heterozygote, character and phenotype, dominance and recessivity, Mendel's laws, monohybrid and dihybrid crosses, autosomal and gonosomal inheritance, reading pedigree charts, genetic tasks and probability calculations, and human genetics
• Mutations, karyotypes and DNA technology: mutations and their types including silent, missense, nonsense and frameshift, the karyotype, chromosomal aberrations, Barr bodies and the syndromes associated with abnormal sex-chromosome counts, DNA technology and the basics of the human genome
• Tissues and the musculoskeletal system: homeostasis and its maintenance, the tissues of the human body and the types of epithelium, the skeleton and its parts, the vertebral column and its regions, the classification of joints, and skeletal muscles and their action with agonists, antagonists and synergists
• Blood, circulation and immunity: body fluids, blood and its cellular and plasma components, blood groups and transfusion, the immune system and defence mechanisms, the circulatory system and its function, the chambers and valves of the heart, systole and diastole, and lymph and its circulation
• Respiration, digestion and excretion: the respiratory system and its function, lung volumes and vital capacity, the digestive system and nutrition, the digestive organs and the pH of their secretions, bile and pancreatic secretion, the urinary system and kidney function, the excretory system, the skin and its functions, and body temperature and its maintenance
• Nervous system, senses and endocrine glands: the nervous system and its central and peripheral organisation, the roots of the spinal nerves and afferent and efferent fibres, sympathetic and parasympathetic effects, the senses, the endocrine glands, and hormones and hormonal regulation including the pancreatic hormones
• Reproduction and human development: human reproduction and the male and female reproductive organs and their sequence, gametogenesis, sexual reproduction and fertilisation, human embryonic and foetal development, and the hormones of pregnancy and the placenta
• Evolution and the origin of life: the origins of life and of the cells, chemical evolution, palaeontological evidence of the earliest forms of life, the basics of evolution, Darwinian evolution, the classification of living systems, and acellular organisms
• Ecology and the biosphere: abiotic and biotic factors, the biosphere, ecosystems, population explosion, and building a sustainable society

The ten lettered sections A to J of the official Physics syllabus, reproduced one for one with no regrouping. The syllabus requires each principle to be applied in simple examples and calculations, and states that knowledge of the basic SI units is unavoidable.

• Units, scalars and vectors: the fundamental and derived SI units, the standard prefixes for multiples and submultiples, recognising dimensionless units, substituting one unit expression for another, scalars and vectors, and the addition of vectors
• Mechanics of particles and rigid bodies: uniform rectilinear motion, uniformly accelerated motion with the calculation of position, velocity and acceleration, free fall, Newton's laws of motion, force, momentum, the impulse of a force, weight, density, torque and the equilibrium of moments, static and kinetic friction, uniform circular motion with frequency, angular frequency and centripetal acceleration, work, power, efficiency, kinetic energy, the potential energy of a body in a gravitational field and the conservation of energy, elasticity with normal stress, linear strain, Hooke's law and the modulus of elasticity, Newton's principle of universal gravitation, gravitational acceleration and the potential of the gravitational field
• Oscillations, waves and sound: period, frequency and phase velocity, the instantaneous displacement, velocity and acceleration of an oscillating body, travelling and standing waves, transverse and longitudinal waves, constructive and destructive interference, the intensity of wave motion, a mass oscillating on a spring, the oscillating pendulum, audible sound and ultrasound, and sound intensity with the level of sound intensity in decibels
• Mechanics of fluids: the ideal or perfect liquid, pressure and its units, Pascal's principle, hydrostatic pressure, the hydraulic press, Archimedes' principle and the force of buoyancy, viscosity, laminar and turbulent flow, the equation of continuity, Bernoulli's equation and efflux speed, surface tension, capillary elevation and depression, and the pressure in a bubble with Laplace's formula
• Principles of thermodynamics: thermodynamic systems, states and processes, reversible and irreversible processes, thermodynamic (Kelvin) temperature, the ideal gas law and the universal gas constant, pV-diagrams, the equations for isothermal, isosteric, isobaric and adiabatic processes, the thermal expansion and contraction of solids, heat, heat capacity and specific heat capacity, the first law of thermodynamics, the equation of thermal conductivity, latent heats and boiling under changed pressure, the second law of thermodynamics and the working cycle of the ideal Carnot engine, and absolute and relative air humidity
• Electricity and circuits: electric charge and conductors, Coulomb's law, the dielectric constant, electric field intensity, potential and potential difference, the capacity of a parallel-plate capacitor, capacitors in parallel and in series, electric current, Ohm's law, resistivity, conductivity and the temperature coefficient of resistance, Kirchhoff's laws, resistors in parallel and in series, electrical power and the heating effect, the thermoelectric phenomenon, Faraday's law of electrolysis and the Faraday constant, N-type and P-type semiconductors, the properties of the P-N junction, and the principle of a transistor
• Magnetism and electromagnetism: the force acting between two magnetic poles, magnetic permeability, magnetic flux and flux density, magnetic force, the magnetic field due to a straight wire or a coil, the force on a conductor carrying a current, Fleming's rule, the force between two parallel conductors, the SI definition of the ampere, the magnetic deflection of a moving electron, electromagnetic induction, Lenz's law, the voltage induced in a straight wire, the self-inductance of a coil, alternating current, the effective values of current and voltage, the electric power of alternating current, impedance including capacitance and inductance, and the AC transformer
• Optics: the basic properties of light and of optical media, the speed of light, reflection and refraction, Snell's law, the critical angle and total internal reflection, lenses, the lens-maker's equation and the sign convention, dioptric power, converging and diverging lenses, the lens equation, linear magnification, the mirror imaging equation and magnification, the basic optical properties of the human eye, the microscope and its magnification, the light spectrum, the interference of light, polarised light, and photometry with luminous intensity, luminous flux and illumination
• Theory of relativity: the dilation of time, the contraction of length, the relativistic addition of velocities, relativistic mass, and the principle of the equivalence of energy and mass
• Quantum, atomic and nuclear physics: the electron volt, the mole and Avogadro's constant, the excitation of atoms, de Broglie matter waves, the principal, orbital and magnetic quantum numbers, Pauli's exclusion principle, emission and absorption spectra, the principle of the X-ray tube, the photoelectric effect, Compton scattering, the structure of the atomic nucleus, nuclides and isotopes, nuclear binding energy, the principle of a nuclear reactor, alpha, beta and gamma decay, neutron radiation, the fission of heavy nuclei, the law of radioactive decay and half-life, the becquerel, and the Geiger-Mueller counter

It's the entrance test Masaryk University's Faculty of Medicine uses to select candidates for its English-taught General Medicine programme in Brno. It is three separate written tests (Chemistry, Biology and Physics) of 40 multiple-choice questions each, 50 minutes per test, 120 questions and 150 minutes in total. Every item has five possible answers with exactly one correct.

Neither. There is no national Czech medical entrance test, and Masaryk is a separate university from Charles; its paper has nothing structurally in common with Charles University's five faculties beyond the subjects. Masaryk runs three equal 40-question tests with a published pass mark; Charles University's Hradec Králové faculty runs one 60-question paper with unequal 25/25/10 weights and an elective; its Pilsen faculty runs three compulsory sciences with part of the paper open-response; its Prague faculties run different papers again. Preparation built for one does not transfer cleanly.

In person, in English, sat through Masaryk University's official representatives in the listed countries. A simple calculator is permitted, and no periodic table or other reference material is supplied: anything you would want to look up needs to already be in your head.

The Faculty publishes a pass mark but not a marking scheme: the Call states no point value for a correct answer, no penalty and no rule for blanks, and the official sample papers carry no marking instructions either. IvyTest models the paper as +1 for a correct answer and 0 for everything else, because that is the neutral assumption. On that model a blind five-option guess is worth +0.20 marks and a blank is worth 0, so there is no item worth leaving empty, and narrowing an item to three options before guessing lifts its return to about +0.33 marks.

The Call states that the acceptance pass mark in General Medicine is 60%, and 65% for Dentistry. It does not say whether that percentage is computed across all 120 questions or separately within each 40-question test, and it publishes no raw-score equivalent. The practical resolution is that the per-test reading is strictly stricter (any set of scores with at least 24 out of 40 in every test necessarily totals at least 72 out of 120), so planning to clear 24 in each subject satisfies both readings at once.

No. The Call is explicit that passing does not guarantee a place: the Dean sets the number of places available, higher scorers take priority, and lower scorers are offered places only if higher scorers decline. The pass mark keeps you in consideration; your rank within the cohort is what actually decides the outcome.

Not within the same cycle. The Call states that an applicant may sit the entrance examination only once per admission year, so there is no second session to hold anything back for, unlike some Italian private schools, which run two sittings and count the better score.

English. The programme is English-taught and all three tests are sat in English, as are the Faculty's official sample papers. Czech is taught during the degree because clinical placements from around the second year involve Czech-speaking patients, but no Czech is required to sit the entrance examination.

The Faculty publishes no seat count for the English-taught programme: the Dean sets the number of places each cycle. Masaryk University's admissions report for 2025 gives the clearest picture: 467 applied to General Medicine in English, 400 sat the exam and 352 were admitted, about 75% of applicants and 88% of those who sat. Places go to higher scorers first, so aim for a margin above the 60% bar rather than the bar itself. Its report for 2026 is not out yet (checked 16 October 2026).

Within the EU, yes: automatically, as a standard Czech medical degree. There's no separate national licensing exam afterwards: the Czech state exam (státní rigorózní zkouška) is built into the MUDr degree itself, and registration with the Czech Medical Chamber (ČLK) is compulsory to practise in the country. Outside the EU recognition isn't automatic as a rule, but the UK is an exception. Under the Medical Act 1983 (section 21B, as in force on 12 October 2026), a Czech medical degree (MUDr.) is a 'relevant European qualification', so a graduate who applies to the GMC with one, whatever their nationality, is not asked to show the knowledge and skills other international graduates prove through PLAB/UKMLA; evidence of English is still required, and the rule is UK policy that can change. US-bound graduates need ECFMG certification via USMLE Step 1 and Step 2 CK, the same requirement every international medical graduate faces.

Yes. The IvyTest simulator runs Masaryk-format practice (three separately timed 50-minute tests of 40 five-option questions in Chemistry, Biology and Physics) in timed, tutor and review modes, with per-test analytics against the 60% bar and a free diagnostic available without payment.

Masaryk publishes no past papers, but its Entrance Exam Preparation page links free PDFs: one sample test per subject (Biology A, Chemistry A and Physics A, labelled 2022, 40 five-option questions each) and the official syllabus for each subject. The sample tests come without answers or marking instructions. The Faculty also sells e-learning preparatory courses in Biology, Chemistry and Physics, €100 each, which end in final tests similar to the real exam. Because the official samples come without answers, IvyTest has written a free full-length sample test in the same format (Chemistry, Biology and Physics, 40 five-option questions each), with every answer explained.

There is no single date: you apply through one of the Faculty's official representatives and sit the exam on one of its dates. The e-application for 2027/2028 is open from 2 January to 31 July 2027, and each sitting closes about two weeks before it. Dates published so far run from 18 January 2027 (Israel) and 30 January 2027 (India, Qatar, UAE) to 17 July 2027 (Portugal). Non-EU applicants must sit by April, exceptionally May; June and July are for EU citizens.

Completed secondary education with a final certificate or diploma (three A-levels or the IB, for example), recognised in the Czech Republic before enrolment for a CZK 990 fee, and a pass in the three entrance tests, which you may sit once per admission year. No English certificate, motivation letter or references are asked for. Strong MCAT/DAT, PACES/MMOP, A-level, IB, Abitur or Swiss results can replace the exam. Non-EU students also need a long-term visa and should apply as soon as their admission documents arrive.

Tuition for General Medicine is CZK 380,000 per academic year (about €15,300–15,700), payable in two instalments, one per semester. The Faculty lists no application fee; it names a CZK 990 fee for recognising your secondary education and keeps CZK 25,000 if you pay tuition and then do not enrol. From the third semester, students with a 1.0 grade average can win the Dean's Merit Scholarship, 50% off the next semester's tuition. Living costs: halls about €200 a month, meals about €8 a day.

Six years in English, leading to the MUDr. (equivalent to an MD). The first two years are mainly theoretical: Biology, Biophysics, Chemistry and Biochemistry, Anatomy with dissection, Histology and Physiology, with First Aid and Czech for Foreigners from the first semester. Clinical teaching follows in Brno's hospitals, including University Hospital Brno and St. Anne's, with training at the SIMU simulation centre, four blocks of summer practice, a final year of pre-graduation practice and state exams in five subjects.

Masaryk reports university-wide places, not a table for medicine alone: 454th in the QS World University Rankings published in June 2026 (third in the Czech Republic), 601-650 in the Times Higher Education World University Rankings published on 1 October 2026, and 401-500 in ShanghaiRanking's ARWU 2026, sharing first place in the Czech Republic. IvyTest has not checked the tables itself. The Faculty states that its degrees are recognised in the EU and the USA and that it is listed in the World Directory of Medical Schools.

In Brno, the Czech Republic's second-largest city. The Faculty is on the University Campus Bohunice, next to the CEITEC research centre and its SIMU simulation centre, and its International Studies Office is at Kamenice 753/5. Clinical teaching runs in Brno's hospitals, including University Hospital Brno and St. Anne's University Hospital. The entrance exam itself is sat through the Faculty's official representatives in their countries, from Georgia and India to the UK and Thailand.

No. The TSP (Test studijních předpokladů) is Masaryk University's study-aptitude test for admission at almost all of its faculties: three parts of 15 questions in numerical and analytical thinking, reasoning in English and critical thinking. The university names the Faculty of Medicine as one of the exceptions: its applicants sit subject tests instead, and for General Medicine in English that means the three science tests of 40 questions each described above.

IvyTest publishes no student reviews of its own. The Faculty lists Student Ambassadors, twelve current General Medicine students from different countries whom you can email, and points applicants to MIMSA, the Masaryk International Medical Students Association, which is run by international students from higher years and whose Education Team offers tutoring to new students.

Yes: r/MasarykUniversity, where Masaryk University applicants ask each other about the Masaryk University Entrance Exam and share how their preparation is going. It is run by the IvyTest team. Dates, rules and results come only from the university's own pages, listed under Official sources on this page.

r/MasarykUniversity