Charles University Pilsen Entrance Exam 2027: Complete Preparation Guide

The faculty's own four areas are General and Cell Biology, Genetics and Heredity, Human Biology and Ecology. The sample paper is entirely text-based, with no figures anywhere.

• Foundations and classification: the landmark figures and what each is attached to: Hooke, van Leeuwenhoek, Schleiden, Purkyně, Harvey, Vesalius, Malpighi, Mendel, Darwin, Pasteur, Koch, Fleming, Morgan, Watson and Crick, Röntgen; taxonomy and the biological species, taxonomy of vertebrates and of humans, the hierarchy of living systems, acellular, unicellular and multicellular organisation, Darwinian evolution, variability, mutation, selection, genetic drift, gene flow, prebiotic and cellular evolution, the milestones of human evolution
• Cell structure: cell theory and cell size, prokaryotic versus eukaryotic cells, plant versus animal cells, the chemical composition of the cell including proteins, nucleic acids, saccharides and lipids, nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, ribosomes, centrioles, cytoskeleton, chloroplasts and other plastids, biomembranes, and surface specialisations such as microvilli
• Transport and cell energetics: diffusion, osmosis, active transport, endocytosis, pinocytosis and phagocytosis, photosynthesis, cellular respiration, glycolysis and oxidative phosphorylation, and why photosynthesis and respiration are complementary at both cellular and ecosystem level
• Cell cycle, mitosis and meiosis: the phases of the cell cycle and their regulation, the phases of mitosis, regulation and errors of mitosis, the phases and biological significance of meiosis, and the comparison of mitosis with meiosis by purpose, number of divisions, daughter cells and genetic variation
• Chromosomes and gene expression: the human karyotype, chromosome structure and classification, gamete maturation and sex determination, the structure and function of nucleic acids, intranuclear and extranuclear DNA, the RNA types and where RNA is synthesised, DNA replication, transcription, translation, the genetic code, genome, chromosome and gene structure, and the regulation of gene expression
• Inheritance and medical genetics: genotype and phenotype, dominant and recessive alleles, homozygous and heterozygous states, complete and incomplete dominance, codominance, Mendel's laws, linkage and gene interactions, gene, chromosomal and genomic mutations with their causes and consequences, autosomal dominant and recessive traits, sex-linked inheritance and pedigree logic, multifactorial traits, medically important chromosomal abnormalities, and the links to hereditary disease and cancer
• Tissues, blood and immunity: epithelial, connective, muscular and nervous tissue, ectoderm, endoderm and mesoderm differentiation, total body water, extracellular and intracellular fluid, plasma composition, erythrocytes, leukocytes and thrombocytes with their functions and counts, blood volume, haematocrit, the ABO and Rh systems, agglutination, agglutinogens and agglutinins, transfusion and the universal donor and recipient, and B lymphocytes and antibody defence
• Musculoskeletal and integumentary systems: the axial and appendicular skeleton, bone structure and development, osteoblasts and periosteum, joints and articulations, cartilage and chondrocytes, skeletal muscle structure and fasciae, motor units and the contraction mechanism, and the skin with its sebaceous, sweat and ceruminous glands
• Circulation and respiration: the location of the heart, its chambers, valves and conduction system, heart rate and its control centre, the pulmonary and systemic circulations and where each begins and ends, arteries, veins and capillaries, blood pressure, the lymphatic system, lymph nodes and spleen, the conducting passages and lungs, ventilation, gas transport, and external and internal respiration and gas exchange
• Digestive, excretory and endocrine systems: the organs and glands of the digestive tract, the liver and bile, nutrients and vitamins, the digestion and absorption of carbohydrates, proteins and fats, the functions of the urinary system, urine production and composition, kidneys, ureters, bladder and urethra, the classification of glands and the nature of hormones, adenohypophysis and neurohypophysis, thyroid, parathyroids, pancreas, adrenals and gonads with their principal hormones
• Nervous and sensory systems: neurons and neuroglia, peripheral nerves, the somatic and autonomic divisions, spinal cord, brainstem, pons, midbrain, medulla oblongata, cerebellum, diencephalon and cerebral hemispheres, reflexes, excitability, resting and action potentials, synapses, and smell, taste, skin perception, the eye, the vestibular apparatus and hearing
• Ecology: the scope and definition of ecology, the hierarchy from organism through species, populations, communities, ecosystems and biomes to the biosphere, biodiversity, habitat, biotope and niche, biotic and abiotic factors, population, community and ecosystem ecology, food chains and food webs, trophic levels, producers, consumers and decomposers, and atmospheric composition and terminology

The faculty's two official areas are General and Inorganic Chemistry, and Organic Chemistry and Biochemistry. Roughly half the sample items are calculations or open-response tasks, and one item shows a ring structure as a figure.

• Atomic structure and radioactivity: the definition of the atom, atomic number and mass number, protons, neutrons and electrons with their charges, masses and locations, electron configurations, isotopes and isotones, radioactivity and radioactive decay, and atomic, molecular, molar and relative mass
• Amount of substance and stoichiometry: molar mass, the mole, the Avogadro constant, particle counting, the relationships among mass, molar mass, amount and number of particles, unit conversions, stoichiometric calculation, and balancing equations by conservation of atoms
• Chemical bonding and intermolecular forces: the strong bonds (covalent, ionic and metallic) and the weak interactions (hydrogen bonds, Van der Waals forces and hydrophobic interactions); intermolecular forces in solids, liquids and gases, and hydrogen bonding in biological molecules
• The periodic table and main groups: the arrangement of the table, periods and groups, element symbols, electron configurations and periodic properties, hydrogen and the alkali metals, the alkaline-earth metals, the boron and carbon groups, the nitrogen family, chalcogens, halogens and noble gases, valence electrons, the important compounds of each group and the biological relevance of key elements
• Inorganic nomenclature and oxidation states: oxides, hydroxides, inorganic acids, halides, sulphides, cyanides, nitrates, sulphates, hydrogen carbonates, phosphates and hydrides, naming compounds from formulas and writing formulas from names, assigning oxidation states in neutral compounds and in ions, and building ionic formulas by balancing cation and anion charge
• Mixtures, solutions and concentration: solute and solvent, solubility, mass fraction, molarity and mass concentration, dilution, dissociation, electrolytes and nonelectrolytes, suspensions and emulsions, sedimentation and stability, and density, mass and volume relationships including conversions between g/cm³ and kg/m³
• Chemical reactions, kinetics and redox: synthesis, decomposition, single and double replacement, condensation and hydrolysis reactions, the factors affecting reaction rate, catalysts, the equilibrium constant, redox reactions, oxidising and reducing agents, and balancing redox equations
• Acids, bases and pH: protolytic reactions, acids, bases and amphoteric compounds, hydrogen ion concentration and pH, strong versus weak acids and bases, pH calculation for strong monoprotic acids, neutralisation, titration and dissociation constants
• Organic structure and isomerism: molecular, empirical and structural formulas, the valence of carbon, hydrogen, oxygen, nitrogen and the halogens, saturated and unsaturated hydrocarbons, aliphatic and aromatic compounds, single and multiple bonds, isomerism, optical activity with levorotary and dextrorotary rotation and the R/S and D/L terminology, and the common halogen derivatives
• Functional groups and derivatives: thiols, alcohols, phenols, ethers, aldehydes, ketones and quinones, mono-, di- and tricarboxylic acids, salts, esters, amides, anhydrides, acid halides and nitriles, fatty acids such as palmitic, stearic and oleic acid, and naming and recognising each group with its typical reactions
• Heterocycles, amines and amino acids: furan, imidazole, indole, purine, pyridine, pyrimidine, pyran and pyrrole and their relevance to nucleic acids and biomolecules, amine nomenclature and the primary, secondary and tertiary classification, choline, epinephrine, norepinephrine, dopamine, serotonin and histamine, and amino acid formulas, classification, properties and reactions
• Biomolecules: saccharides and their D and L enantiomers, reactivity and the key mono-, di- and polysaccharides, lipids, triacylglycerols, phospholipids, steroids, cholesterol, lecithin and sphingomyelin, proteins and their primary, secondary, tertiary and quaternary structure, nucleic acids with bases, nucleosides, nucleotides and complementary base pairing, DNA and RNA, and the vitamins

The faculty's five official areas are Units and Quantities, Mechanics, Thermodynamics, Electricity and Magnetism, and Optics and Acoustics. Gravitation is folded in with forces and rotation, and the sample paper supplies its own table of constants for calculation items.

• Units, quantities and dimensions: the SI, CGS and MKS systems, base and derived SI units, the common prefixes, conversions of length, area, volume and density, the density of water, expressing derived units such as Pa, N, J, W, C, V and the ohm in base units, scalar and vector quantities, and checking a formula through its dimensions
• Linear motion: uniform linear motion, distance, time and velocity, the distinction between speed and velocity, accelerated motion, free fall, acceleration and gravitational acceleration, the conversion of km/h to m/s, and position, velocity and acceleration calculations
• Forces, rotation and gravitation: Newton's laws, force as a vector, momentum and impulse, mass and weight, torque, uniform circular motion, frequency and angular frequency, centripetal acceleration, Newton's law of universal gravitation, gravitational force, the gravitational constant and the dependence on distance
• Work, power and energy: work and energy with their SI units, mechanical work calculations, power in mechanical and electrical form, mechanical efficiency, mechanical energy, kinetic energy, gravitational potential energy and changes in it
• Fluids: the ideal liquid, pressure and hydrostatic pressure, Pascal's principle, atmospheric pressure, Archimedes' principle and buoyant force, volume, mass and density, flow and the continuity equation, Bernoulli's law, viscosity, laminar and turbulent flow, and surface tension
• Thermodynamics and heat: thermodynamic systems, states and processes, the Celsius and Kelvin scales, absolute zero, normal body temperature, the first and second laws of thermodynamics, the ideal gas law and the gas constant, isobaric, isothermal and isochoric processes, the laws of Boyle, Charles, Avogadro and Gay-Lussac, thermal expansion and contraction, heat, heat capacity, specific heat capacity and its units, and calorimetry
• Electrostatics and capacitance: electric charge and its units including the ampere-hour, electrostatic attraction and repulsion, the electron and proton charge, Coulomb's law, electric field intensity, potential and potential difference, capacitance, parallel-plate capacitors, and capacitors in series and parallel
• Current electricity and circuits: electric current and its SI unit, Ohm's law, current, voltage and resistance, resistors in series and in parallel, cells connected in series and in parallel, electric power and the relation between power, current and voltage, and everyday appliance calculations
• Magnetism, induction and alternating current: Faraday's law of electrolysis and the Faraday constant, magnetic force, permeability, magnetic flux and flux density, the magnetic field and Ampère's rule, electromagnetic induction, Faraday's and Lenz's laws, Fleming's rule, alternating current, effective current and voltage, AC power, impedance, inductance and transformers
• Light, optics and photons: the properties of light, speed, wavelength, spectrum and frequency, visible, ultraviolet and infrared light, photon energy from frequency, the photoelectric effect and the particle theory of light, reflection, refraction, refractive index, Snell's law and the critical angle, mirrors and lenses, refractive power, the lens and imaging equations, magnification, interference, polarisation, luminous intensity, luminous flux, illumination and the optics of the eye
• Sound and acoustics: the production, control, transmission, reception and effects of sound, frequency, wavelength and the speed of sound, sound pressure and sound pressure level, intensity and intensity level, the human hearing range, noise, pitch, loudness, timbre, sonic texture and spatial location, and ultrasound above 20 kHz and infrasound below 20 Hz

Three compulsory science subjects, Biology, Chemistry and Physics, 20 questions each and 60 in total for 2027/28, every one with a single correct answer worth one point. It is the written test the Faculty of Medicine in Pilsen uses for its English-taught General Medicine and Dentistry. The faculty's syllabus splits Biology into four areas, Chemistry into two and Physics into five; there is no logic or reading section.

Neither. There is no national Czech medical entrance test, and Charles University's five medical faculties run structurally different papers. Pilsen runs Biology, Chemistry and Physics; the First Faculty in Prague has no Physics section at all and examines Biology, Chemistry and General Science; the Second Faculty runs four sections including Logic; the Third Faculty runs only Biology and Chemistry. Hradec Králové is closest to Pilsen in subject matter but lets candidates choose Mathematics instead of Physics and weights that third subject at only 10 of 60 marks. Preparation built for one faculty does not transfer cleanly to another.

In person, in English: in Pilsen or at a sitting run by one of the faculty's cooperating agencies abroad. The 2027/28 admission criteria allow an online test only with the Dean's approval, in cases of force majeure or a serious medical condition, requested through your application in the SIS. The official sample papers supply their own table of physical constants for calculation items, which is a fair indication of what you can expect to be given on the day.

One point for each correct answer, and no penalties in case of mistakes: that is stated on the faculty's admission page and in the programme's 2027/28 admission criteria, even though the sample answer keys list correct answers only. A blind four-option guess is therefore worth about +0.25 marks while a blank is worth 0, so there is no question worth leaving empty, least of all in a subject close to the 9-point minimum.

Unknown. IvyTest re-checked the faculty's admission page, the three official sample-test PDFs and the programme's 2027/28 admission criteria in full on 11 October 2026 and none of them states a time limit. A 90-minute figure circulates online with no traceable source behind it, so it should not be treated as a faculty figure. Practise to a self-imposed limit and keep it constant so your own results stay comparable.

At least 9 of the 20 points in each of Biology, Chemistry and Physics, a minimum new in the 2027/28 admission criteria, and then the total the Dean sets according to the anticipated number of admitted students. That total is not published in advance and no figure appears on the faculty's own site, so aim for a comfortable margin in all three subjects rather than a number.

The live paper is: the admission criteria say there is always only one correct answer, worth one point. The official sample papers are not, though. Most sample items give four options A to D, but a substantial minority are open-response (short definitions, calculations, balancing equations and naming compounds), including 6 of the Chemistry sample's 20 items (about 30%). They are worth working as recall practice, because producing an answer is a stronger test of knowledge than picking one.

English. The programme is English-taught and the official sample tests are in English throughout. No Czech is required to sit the entrance examination. During the degree, practical training in hospitals and GP offices runs from the second year, and besides Latin every student must pass an examination in English and one more foreign language.

For 2027/28 Charles University's admissions records list 105 General Medicine places and 28 in Dentistry. In the past academic year 99 of 298 General Medicine applicants and 27 of 87 Dentistry applicants were admitted, about 33% and 31%. For 2026/27 the records had listed about 90 General Medicine places (at most 105) and 14 in Dentistry (at most 24).

Within the EU, yes: automatically, as a standard Czech medical degree. There's no separate national licensing exam afterwards: the Czech state exam (státní rigorózní zkouška) is built into the MUDr degree itself, and registration with the Czech Medical Chamber (ČLK) is compulsory to practise in the country. Outside the EU recognition isn't automatic as a rule, but the UK is an exception. Under the Medical Act 1983 (section 21B, as in force on 12 October 2026), a Czech medical degree (MUDr.) is a 'relevant European qualification', so a graduate who applies to the GMC with one, whatever their nationality, is not asked to show the knowledge and skills other international graduates prove through PLAB/UKMLA; evidence of English is still required, and the rule is UK policy that can change. US-bound graduates need ECFMG certification via USMLE Step 1 and Step 2 CK, the same requirement every international medical graduate faces.

Yes. The IvyTest simulator runs Pilsen-format practice across Biology, Chemistry and Physics in the real four-option format, in timed, tutor and review modes, with a free diagnostic available without payment. Because part of the official sample papers is open-response, use the simulator alongside closed-book recall work rather than instead of it.

The faculty publishes no past papers. Its admission page links three free sample tests as PDFs, one each for Biology, Chemistry and Physics, 20 questions apiece with the solutions at the end: most items have four options A to D, some are open-response. The same page sets out the full syllabus of each subject and a short list of A-level study guides as recommended books.

Applications for 2027/28 run from 1 November 2026 to 30 April 2027, online with the application fee, and later applications are not accepted. The exam is held in Pilsen on 26 May 2027, with an alternative date on 28 June 2027; the cooperating agencies' sittings abroad run from May to August, dates still to be announced. Results follow within a week, and enrolment is in July and September 2027.

The faculty lists four: an online application by the deadline, the entrance exam, proof of secondary education with a school-leaving examination, and the tuition fee. The faculty's list of requirements includes no English certificate, interview or motivation letter. Admitted students send their legalised and translated school documents by 31 August 2027 and, at enrolment, a medical certificate with proof of hepatitis B and measles vaccination. You may apply once per academic year, and transfers are not accepted.

Tuition for 2027/28 is CZK 390,000 a year for General Medicine and CZK 410,000 for Dentistry, paid in full before enrolment, with no instalments for first-year students. The application fee is CZK 1,000 in Charles University's admissions records (CZK 990 on the faculty's page), and the school-document assessment CZK 1,050. It is not an MBBS: General Medicine leads to the MUDr. degree after six years, Dentistry to the MDDr. after five.

Six years. The first two cover theoretical subjects such as Anatomy, Histology, Embryology, Biophysics, Biochemistry and Physiology; years 3 and 4 the preclinical ones, among them Pathological Anatomy, Pathological Physiology, Microbiology, Immunology and Pharmacology, with bedside teaching from year 3; the last two years are wholly clinical. Practical training in hospitals and GP offices runs from year 2, and the campus beside University Hospital Pilsen has a Simulation Center.

The faculty quotes no QS or other ranking position for itself, and IvyTest has not checked any ranking table. Its own pages say it is one of Charles University's five medical faculties, that Charles University is among the top 1.5% of universities in the world and one of the oldest in Europe, and that it moved in 2022 to the most modern medical campus in the country. It was founded in 1945 and has around 2,000 students, 500 of them from abroad.

IvyTest publishes no student reviews of its own. What the faculty publishes about student life is on its Life in Pilsen page: a city 50 minutes from Prague and from Germany, a university dorm at €160 a month, a private dorm at €500, a university meal at €4 and a public-transport card at €12 a month. Its Facebook, Instagram and YouTube channels and its student associations are linked from every page of its site.

The science is at school-leaver level (the faculty recommends A-level study guides), but three full subjects with no logic or reading section to lean on, a 9-point minimum in each 20-question subject, open-response items in the official samples and an unpublished time limit make it demanding. In the past academic year 99 of 298 General Medicine applicants were admitted, about one in three.

Yes: r/CharlesPilsen, where Charles University, Faculty of Medicine in Pilsen applicants ask each other about the Charles University Pilsen Entrance Exam and share how their preparation is going. It is run by the IvyTest team. Dates, rules and results come only from the university's own pages, listed under Official sources on this page.

r/CharlesPilsen